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R3 Vascular raises $17.8m for devices to treat peripheral artery diseases

R3 Vascular, an early-stage US medical device company, has raised $17.8 million in a Series A financing round, led by an undisclosed corporate investor and 415 CAPITAL. The funding comprised new equity investments of $15 million and the conversion of $2.8 million of convertible notes. The Series A round also saw participation from HBM-MedFocus and Wexford […]

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Apellis reports positive results for pegcetacoplan in phase 2 C3G trial

Apellis Pharmaceuticals has reported positive results for pegcetacoplan from the phase 2 DISCOVERY clinical trial in patients with C3 glomerulopathy (C3G), a type of kidney disease. According to the US biopharma company, the 48-week results demonstrated that patients subjected to pegcetacoplan had sustained improvements across key clinical measures. These include a greater than 65% mean […]

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Bristol Myers Squibb to acquire MyoKardia to gain access to mavacamten

Bristol Myers Squibb (BMS) has agreed to acquire California-based clinical-stage biopharma company MyoKardia for $13.1 billion, to gain access to the latter’s cardiovascular drug candidate mavacamten. The US pharma giant is offering to acquire MyoKardia for $225.00 per share in an all-cash deal. Mavacamten is being developed for the treatment of a chronic heart disease […]

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AstraZeneca gets FDA breakthrough status for Farxiga in CKD

AstraZeneca has been granted breakthrough therapy designation (BTD) for Farxiga (dapagliflozin) from the US Food and Drug Administration (FDA) for the treatment of patients with chronic kidney disease (CKD), irrespective of type 2 diabetes (T2D). According to the US Centers for Disease Control and Prevention (CDC), chronic kidney disease is a serious, progressive condition defined […]

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Dr. Reddy’s launches Sapropterin Dihydrochloride Tablets generic version in US

Indian pharma company Dr. Reddy’s Laboratories has launched a generic version of phenylalanine hydroxylase activator Sapropterin Dihydrochloride Tablets, for oral use, in the US market. Sapropterin Dihydrochloride Tablets are indicated in the US for reducing blood phenylalanine (Phe) levels in adult and pediatric patients, aged one month and older with hyperphenylalaninemia (HPA) due to tetrahydrobiopterin- […]

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Covis Group to acquire US biopharma company AMAG Pharmaceuticals

Covis Group, a Luxembourg specialty pharma company, has agreed to acquire US biopharma company AMAG Pharmaceuticals for about $647 million, which includes the latter’s debt. As per the terms of the deal, Covis Group will acquire AMAG Pharmaceuticals for $13.75 per share in cash, or nearly $498 million. Covis Group is making the acquisition to […]

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OliX Pharmaceuticals seeks FDA nod for phase 2a trial of OLX10010

OliX Pharmaceuticals, a South Korean pharma company, has submitted an investigational new drug (IND) application to the US Food and Drug Administration (FDA) seeking its consent to begin a phase 2a clinical trial for OLX10010 in reducing the recurrence of hypertrophic scars after scar revision surgery. The developer of RNAi therapeutics intends to assess the […]

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Millendo Therapeutics begins human trial of VMS drug candidate MLE-301

Millendo Therapeutics has started a phase 1 clinical trial of its selective neurokinin 3 receptor (NK3R) antagonist MLE-301, which is being developed for the treatment of menopausal women with vasomotor symptoms (VMS). VMS is known commonly as hot flashes and night sweats in menopausal women. The Michigan-based biopharma company has dosed the first subject in […]

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J&J begins phase 3 ENSEMBLE Covid-19 vaccine trial for JNJ-78436735

ENSEMBLE Covid-19 vaccine trial : Johnson & Johnson (J&J) has launched a multi-nation phase 3 trial called ENSEMBLE for its JNJ-78436735 Covid-19 vaccine candidate (Ad26.COV2.S), which is being developed by its subsidiary – Janssen Pharmaceutical Companies. The US healthcare giant said that the ENSEMBLE vaccine trial has been initiated following positive interim results from its […]

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Ampersand acquires majority stake in in vitro diagnostics company ALPCO

Ampersand Capital Partners, a middle-market private equity firm, has acquired a majority stake in American Laboratory Products Company (ALPCO), an in vitro diagnostics company, for an undisclosed price. Established in 1990, ALPCO started off as an importer and distributor of immunoassay-based products serving the North American life science markets. Currently, the company offers its proprietary […]

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