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Incyte to launch ruxolitinib coronavirus clinical trial in US

Incyte to launch ruxolitinib coronavirus clinical trial in US

Ruxolitinib coronavirus clinical trial : Incyte revealed that it is working with the US Food and Drug Administration (FDA) to launch the phase 3 RUXCOVID clinical trial to assess the efficacy and safety of ruxolitinib (Jakafi) plus standard-of-care (SoC) in patients with COVID-19 associated cytokine storm syndrome. The ruxolitinib plus standard-of-care will be compared to […]

Japan’s Fujifilm to test anti-flu drug Avigan to treat coronavirus

Japan-based Fujifilm has started clinical trials to test the efficacy of Avigan, an anti-flu drug to treat coronavirus patients. Trials done in China suggested that Avigan might play a key role in reducing the recovery time for patients who reported positive for coronavirus. According to a company’s spokesman, the trial will be done on 100 […]

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RECOVERY coronavirus trial : First patients enrolled in COVID-19 clinical trial by University of Oxford

RECOVERY coronavirus trial : University of Oxford researchers in the UK have initiated a coronavirus clinical trial called the Randomised Evaluation of COVid-19 thERapY (RECOVERY) trial. The RECOVERY clinical trial, which has enrolled the first patients, will test the effects of potential drug treatments for COVID-19 patients admitted to hospitals. The objective of the clinical […]

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Actemra coronavirus clinical trial : Genentech gets FDA nod for COVID-19 trial

Actemra coronavirus clinical trial : Genentech has been given approval by the US Food & Drug Administration (FDA) to undertake the phase 3 COVACTA trial to assess the safety and efficacy of intravenous Actemra (tocilizumab) along with standard of care in hospitalized adults having severe COVID-19 pneumonia. The Roche subsidiary will carry out the randomized, […]

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Coronavirus vaccine trial : Moderna doses first subject with mRNA-1273 in phase 1 trial

Coronavirus vaccine trial : US biotech company Moderna has dosed the first participant in the phase 1 study of mRNA-1273, its mRNA vaccine against the novel coronavirus (SARS-CoV-2). The phase 1 coronavirus clinical trial is being carried out under its own Investigational New Drug (IND) application by the National Institutes of Health (NIH). mRNA-1273 is […]

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Antibe Therapeutics completes patient enrollment in OA knee pain trial for ATB-346

Antibe Therapeutics, a Canadian pharma company has completed enrollment of patients in a phase 2B dose-ranging, efficacy clinical trial of its lead drug candidate ATB-346 for its use in reducing osteoarthritis (OA) pain. The mid-stage clinical study will assess the effectiveness of ATB-346 in the reduction of OA knee pain in comparison to placebo in […]

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COSMIC-311 clinical trial : Exelixis enrolls patients to study cabozantinib in phase 3 thyroid cancer trial

COSMIC-311 clinical trial : US biotech company Exelixis has enrolled the first 100 patients in a phase 3 trial called COSMIC-311 for evaluating cabozantinib (CABOMETYX) against placebo in a type of thyroid cancer. The COSMIC-311 trial will feature patients having radioactive iodine-refractory differentiated thyroid cancer who have progressed following up to a couple of vascular […]

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Reneo Pharmaceuticals launches REN001 clinical trial in McArdle disease

Reneo Pharmaceuticals has initiated a phase 1b clinical trial of REN001 in glycogen storage disease type V (GSD V), also called McArdle disease. The California-based clinical-stage pharma company is currently enrolling participants into the early-stage clinical trial in the UK and Spain. Considered as an inherited disorder, McArdle disease is caused by the body’s inability […]

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KIK-AS clinical trial : Angelman syndrome drug candidate GTX-102 to be evaluated by GeneTx Biotherapeutics

GeneTx Biotherapeutics is set to start the KIK-AS clinical trial for evaluating GTX-102 for the treatment of Angelman syndrome (AS), a rare, neurogenetic disorder resulting from the loss-of-function of the maternally inherited allele of the UBE3A gene. In this connection, the biotech startup has secured institutional review board (IRB) approval from Rush University Medical Center […]

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ImmunogenX enrolls patients for Solutions for Celiac trial of Latiglutenase

ImmunogenX, a subsidiary of Immunogenics, has started enrollment of patients for a phase 2b clinical trial to evaluate Latiglutenase (IMGX003), its lead candidate for the treatment of celiac disease. The mid-stage clinical trial, called Solutions for Celiac trial (NCT04243551) is funded by the US’ National Institutes of Health’s (NIH) National Institute of Allergy and Infectious […]

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